Phosphatidylserine, or phosphatidyl serine as it is written, is a fat-like substance that is one of the few supplements that’s been extensively tested. In clinical studies, it has proven itself a winner by consistently improving memory, concentration, and attention — without side effects.

It actually is able to improve the chemical message signals between neurotransmitters in the brain — the result is a better memory, concentration, etc.

Phosphatidylserine has been scientifically validated to even reverse dementing brain-related illnesses like Alzheimer’s disease and senilty brought on by old age.

Phosphatidyl serine is one of the most powerful nutrients known that can dramatically improve higher cognitive function probably due to its extreme bioavailability as it crosses the blood-brain barrier easily.  

It also affects a wide array of nerve cell functions including conduction of nerve impulses, improving the activity and the number of receptors that are involved with synaptic discharge, as well as other cellular core duties.

Where does it come from?

First, it is a structural component of the membranes of plants and animals. It actually is derived from soy and egg yolks when used for supplementation.

Recommended dosage is 100mg, three times a day.

The Phosphatidyl Cortisol Connection

What about the phosphatidyl cortisol connection? According to researchers, phosphatidylserine appears to lower the production of cortisol, which is a stress hormone that is believed to interfer with memory function.

Cortisol is also believed to interfer with clear thinking.


Researchers believe Phosphatidylserine slows blood clotting so for this reason, it is recommended that those taking anti-coagulants like aspirin or ginkgo biloba should be careful when using it. Pregnant women should consult with their doctor first before taking any supplement.

It is always advised to talk to your physician before beginning any new supplement routine.

Phosphatidylserine Recommendation

This nutrient does work. When looking for it in supplement form, look for it as part of a multivitamin as almost all nutrients are interdependent and co-factors in the proper assimilation of their counterparts.

Also, look for pharmaceutical-grade quality supplements that are produced in GMP-compliant facilities — this will ensure nutraceutical quality, and that’s what you want.

In the US, supplement fraud is rampant as it’s not regulated by the FDA. Of course, there are pros and cons about the FDA regulating nutrients and supplements like phosphatidylserine.

This is still a good guideline, though. Final word? Two thumbs to this unknown, yet remarkable nutrient.

I hope this information has been useful to you.

Yours in health,